Ultrasonic vocalization changes and FOXP2 expression after experimental stroke

Foxp2 mediates sex differences in ultrasonic vocalization by rat pups and directs order of maternal retrieval.

The FOXP2 gene is central to acquisition of speech and language in humans and vocal production in birds and mammals. Rodents communicate via ultrasonic vocalizations (USVs) and newborn pups emit distress USVs when separated from their dam, thereby facilitating their retrieval. We observed that isolated male rat pups emitted substantially more USV calls and these were characterized by a signific...

Vocalization Defects in Conditional Foxp2-KO Mice

Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene.

Neurobiology of speech and language has previously been studied in the KE family, in which half of the members have severe impairment in both speech and language. The gene responsible for the phenotype was mapped to chromosome 7q31 and identified as the FOXP2 gene, coding for a transcription factor containing a polyglutamine tract and a forkhead DNA-binding domain. Because of linkage studies im...

Vocalization Characters and Forkhead Box P2 (FoxP2) Polymorphism in Indonesian Crowing-Type Chicken (Gallus gallus domesticus)

Crowing-type chicken is one of the important chicken breeds in Indonesia. This study was conducted to investigate the crowing characters of Pelung chicken and the effect of exon 7 FoxP2 gene polymorphism in mute chicken. Chicken were obtained from local breeder. Pelung chicken crowing and morphology characterizations were conducted in Cianjur, West Java, Indonesia. Chicken breeding (♀ ...

Rat ultrasonic vocalization: short-range communication

Rodents are subjected to a significant environmental pressure as prey for a large number of carnivore predators. Ultrasonic vocalization is one of the defensive adaptations which minimize the chances of being detected by a predator. Two mechanisms of ultrasound production in the larynx are discussed, with a whistle mechanism being the most probable one. Physical features of ultrasounds, such as...